About Us

About Us

At Medical Discovery Partners LLC (MDP), we focus on the development of innovative medical diagnostics technologies. The company specializes in bringing medical diagnostic research concepts to reality by conducting its own research and then developing the manufacturing methods for transition to commercial production.

The company was founded in 2002, as an outgrowth of the research group from CytoLogix Corporation, Cambridge, MA. The President and co-founder of MDP was also a founder of CytoLogix. In 2002, CytoLogix transferred its ArtisanTM product line to Dako Corporation. The research group formed a new company – MDP – that focuses on technology creation in the area of medical diagnostics.

MDP is located alongside the Department of Pathology and Laboratory Medicine, Tufts Medical Center. As a company located in an academic medical center, it bridges the strengths of academia and industry. MDP brings a technology and product-focused team approach into a medical center academic research environment.

Controls Comparison

  • Reproducibility - IHControls™ are the same day to day over the course of the year. Patient tumors are, by definition, variable and non-standardized.

     

    Antigen retrieval – Formalin-fixed paraffin-embedded tissue controls generally require antigen retrieval, testing an important aspect of the total IHC stain process. The same is true for IHControls™, which also generally require antigen retrieval for optimal IHC staining.

     

    Quantitation – Tissue controls are heterogeneous. IHControls™, on the other hand, were specifically designed for standardized quantitative measurement, facilitating inter-laboratory comparison of staining intensity. IHControls™ include internal negative and positive color standard beads to compensate for differences in microscopy.

     

    Internal specificity checks – Tissue controls have a built-in set of specificity checks, comprising other antigenically irrelevant proteins. IHControls™ also have internal specificity checks, comprising at least one other bead type coupled with an irrelevant antigen.

     

    Role in pre-analytic verification – Leftover paraffin-embedded tissues that were fixed, processed, and embedded at some date in the past do not serve as a control for those processes on future days. The same is true for IHControls™. Neither serve as controls for pre-analytic variables.

     

    Counterstain control – Tissue controls will take up a counterstain. IHControls™ will not, and therefore are not appropriate as a control for a counterstain.

Contact Info

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Medical Discovery Partners LLC
c/o Tufts Medical Center
800 Washington Street
Ziskind 417
Boston MA 02111
P: 617-636-8042
E: first.last@example.com

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